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Enhancing Targeted Next-Generation Sequencing with Cooperative Hybrid-Capture for DNA and Methyl Sequencing (PDF) Agilent Avida NGS hybrid-capture uses efficient cooperative probe binding technology, optimized for low-input samples, providing high molecule recovery and uniform coverage across target regions.

• Publication Part Number: 5994-7815en
• Created: 10 Oct 2024
• 530 KB
• PDF

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Automating Dissolution Testing with an Agilent Online LC System (PDF) In this application note, an Agilent InfinityLab Online LC system was coupled with the Agilent Flexible Cube to enable fully automated,unattended, real-time dissolution testing. The automatic sample delivery and multiple sample point switching...

• Publication Part Number: 5994-7502EN
• Created: 09 Oct 2024
• 968 KB
• PDF

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Analysis of 37 Fatty Acid Methyl Esters on Agilent 8890 GC Using FID and LUMA Detectors (PDF) In this application brief, analyses of fatty acid methyl esters (FAMEs) in a FAME mix standard and store-bought oils were conducted using the Agilent 8890 GC system equipped with an FID and LUMA vacuum ultraviolet decector.

• Publication Part Number: 5994-7849EN
• Created: 08 Oct 2024
• 1 MB
• PDF

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Highly Selective GC/TQ Analysis of 57 Allergens in Cosmetic Products (PDF) Highly selective GC/TQ analysis of 57 allergens in cosmetic products, featuring the Agilent 8890 GC and Agilent 7000E GC/TQ.

• Publication Part Number: 5994-7523EN
• Created: 07 Oct 2024
• 417 KB
• PDF

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Applications

Agilent LUMA Multichannel Vacuum Ultraviolet Detector on Agilent 8890 GC (PDF) In this application brief, the Agilent LUMA multichannel VUV detector was paired with an Agilent 8890 GC and Agilent J&W DB-1 column to demonstrate the analysis capabilities of the system.

• Publication Part Number: 5994-7848EN
• Created: 07 Oct 2024
• 429 KB
• PDF

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Applications

Ultrafast Quantitation of Immunosuppressant Drugs in Whole Blood, Agilent 6475 LC/MS (PDF) Ultrafast quantitation of immunosuppressant drugs in whole blood, Agilent 6475 LC/MS allowing high-throughput analysis of more than 500 samples per day.

• Publication Part Number: 5994-7829EN
• Created: 01 Oct 2024
• 292 KB
• PDF

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Applications

Analysis of Organic Carbonate Solvent Components in Lithium Batteries (PDF) This application note establishes a method for the identification and quantitative analysis of organic carbonate solvent components in lithium battery electrolytes using liquid chromatography coupled to high-resolution quadrupole time-of-flight mass...

• Publication Part Number: 5994-6512EN
• Created: 27 Sep 2024
• 469 KB
• PDF

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Applications

Modernizing the USP Ceftizoxime Sodium HPLC Method Following the Revised USP <621> Guidelines (PDF) The original United States Pharmacopeia (USP) Ceftizoxime Sodium HPLC assay was modernized to take advantage of smaller particle columns, including totally porous particle (TPP) and superficially porous particle (SPP) columns, following the newly...

• Publication Part Number: 5994-7819EN
• Created: 25 Sep 2024
• 304 KB
• PDF

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Applications

LC/MS Based Characterization of GLP-1 Therapeutic Peptide Liraglutide and Impurities (PDF) LC/MS based characterization workflow of the GLP-1 therapeutic peptide liraglutide and its impurities using the 1290 Infinity II LC and 6545XT AdvanceBio LC/Q-TOF.

• Publication Part Number: 5994-7727EN
• Created: 25 Sep 2024
• 3 MB
• PDF

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Applications

Modernizing the USP Acetaminophen and Caffeine Tablets HPLC Method Following the Revised USP <621> Guidelines (PDF) The original United States Pharmacopeia (USP) Acetaminophen and Caffeine Tablets HPLC assay was modernized to take advantage of smaller particle columns, including totally porous particle (TPP) and superficially porous particle (SPP) columns,...

• Publication Part Number: 5994-7820EN
• Created: 24 Sep 2024
• 231 KB
• PDF

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Applications

High-Throughput Analysis of Additive-Elements and Wear Metals in Lubricants by ICP-OES (PDF) Fast analysis times using the Agilent 5900 ICP-OES with AVS and oil autosampler referencing ASTM D5185-18

• Publication Part Number: 5994-7597en
• Created: 23 Sep 2024
• 732 KB
• PDF

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Applications

Analysis of Degradation Impurities of Glucagon-Like Peptide-1 Agonists by LC/Q-TOF MS (PDF) Characterization of forced degradation impurities of glucagon-like peptide-1 agonists by Agilent LC/Q-TOF mass spectrometry.

• Publication Part Number: 5994-7794EN
• Created: 19 Sep 2024
• 822 KB
• PDF

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Applications

High-Throughput Analysis of Wear Metals And Additives in Lubricant Oil Samples (PDF) In this application note, used diesel-engine lubricant oil samples were analyzed in

• Publication Part Number: 5994-7788EN
• Created: 13 Sep 2024
• 497 KB
• PDF

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Determination of mRNA Encapsulation Efficiency with the Agilent 1290 Infinity II Bio LC System (PDF) The study presents an IP-RP-HPLC method for detecting F-luciferase mRNA and highlights the use of isopropanol extraction of lipid nanoparticles (LNPs) to analyze mRNA.

• Publication Part Number: 5994-7778EN
• Created: 13 Sep 2024
• 307 KB
• PDF

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Phase Diagram of the Ouzo Effect Using Temperature-Controlled UV-Vis Spectroscopy (PDF) The Agilent Cary 3500 UV-Vis spectrophotometer, with its Peltier-controlled Multicell module, efficiently established a comprehensive solubility phase diagram for pastis liqueur in a short amount of time, demonstrating its suitability for complex...

• Publication Part Number: 5994-7767EN
• Created: 12 Sep 2024
• 953 KB
• PDF

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Automated Cell Viability Assay (PDF) This application note describes how the Agilent BioTek 406 FX washer dispenser increases a laboratory’s efficiency and productivity by automating the liquid handling steps of the CellTiter-GLO assay.

• Publication Part Number: 5994-6856EN
• Created: 11 Sep 2024
• 573 KB
• PDF

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Applications

Oligonucleotide Mass Confirmation and Impurities Identification (PDF) This application note describes how the Agilent 1290 Infinity II bio LC system, in combination with the MS spectral deconvolution feature in Agilent OpenLab CDS, version 2.8 has been proven to be a reliable and user-friendly tool for oligonucleotide...

• Publication Part Number: 5994-7769EN
• Created: 10 Sep 2024
• 385 KB
• PDF

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Applications

Analysis of Volatile Compounds Identified in Rubber Gasket Extracts Using GC/MSD and High-Resolution GC/Q-TOF (PDF) This application note establishes a process for identifying GC-amenable extractables and leachable compounds using GC/MSD and GC/Q-TOF instruments.

• Publication Part Number: 5994-7777EN
• Created: 10 Sep 2024
• 3 MB
• PDF

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Applications

Ethylene Oxide and 2-Chloroethanol in Spices and Oilseeds Using QuEChERS GC/MS/MS (PDF) This application note demonstrates the use of an Agilent 8890 GC system with 7010 GC/MS to detect and quantify ethylene oxide and 2-chloroethanol in foodstuff.

• Publication Part Number: 5994-7720EN
• Created: 07 Sep 2024
• 1 MB
• PDF

Supporting Documents

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Japanese (Japan)	Complete (PDF)
Korean (Korea)	Complete (PDF)
Chinese (Simplified) (China)	Complete (PDF)

Applications

Verification of Raw Materials for Synthetic Peptide Production with Vaya (PDF) Vaya identification and differentiation of Fmoc protected amino acids for manufacturing of synthetic peptide drugs.

• Publication Part Number: 5994-7610EN
• Created: 04 Sep 2024
• 733 KB
• PDF

Supporting Documents

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Japanese (Japan)	Complete (PDF)
Chinese (Simplified) (China)	Complete (PDF)
Korean (Korea)	Complete (PDF)